Can Hormones Cause Anxiety? Here’s What Experts Say 2024

Christine VanDoren

Updated on - Written by
Medically reviewed by Chelsea Rae Bourgeois, MS, RDN, LD

can hormones cause anxiety
Can hormones cause anxiety?

Many of us experience changes throughout our lives that go unnoticed or under the radar. We often need to recognize these changes as a phase or recognize the seriousness of their effects on our overall health. These changes may come in the form of weight gain, constipation, or excessive thirst, and they may all stem from internal changes related to a hormonal imbalance.[1]

As we explore the causes and symptoms related to hormonal imbalance, we might also consider how hormones affect our mental health. For example, can hormones cause anxiety? We should look beyond physical symptoms and consider potential emotional and mental manifestations, such as hormonal anxiety, to understand the relationship between hormones and anxiety best. 

Here we will discuss remedies for anxiety that can support the nervous system and benefit the brain and body. Effective tools include meditation and mindfulness activities, time outdoors, and the consumption of herbs.

Can Hormone Imbalance Cause Anxiety?

Hormone imbalance can cause anxiety, and it often goes undetected for quite some time. Symptoms that can help you identify a hormone imbalance include mood swings, fatigue, and weight fluctuations. Hormone replacement therapy and cognitive behavioral therapy are common treatment methods; results certainly depend on the individual!

Hormonal Anxiety Symptoms

Worrying And Concentration Loss

One hallmark of hormonal anxiety is uncontrolled feelings of worry and panic. When a threat is registered, whether it’s real or perceived, you may go into anxiety overload and become preoccupied with the threat.

Consider that hormones affect anxiety[2] through chemical interactions, acting on the gut-brain axis. One major hormone, adrenaline, initiates the fight or flight response when you feel danger, resulting in heightened anxiety. Constant activation of this stress response can lead to enduring feelings of fear and anxiety, resulting in a lack of focus and crippling your daily activities. 

Mood Swings

When hormone levels fluctuate, it can impair the efficiency of several biological processes, like mood and stress regulation. Unfortunately, a poor response to outside stressors can cause you to experience significant mood changes, such as extreme highs and lows. With impaired stress management and a decreased focus on what occurs around you, feelings of despair and irritability can develop. 

Fatigue

It’s also important to consider the link between mental and physical health.[3] Disrupted concentration and mood swings can cause sleep disturbances and fatigue. Obsessive worries can prevent you from thinking soundly, relaxing, and getting adequate sleep.

Disturbed sleep and fluctuating moods can diminish your drive to do your daily tasks, and if this becomes more frequent and you lose the will to engage, you might see your physical health decline.

Weight Fluctuations

Unexplained weight loss or weight gain[4] often occurs in hormonal imbalances. This is usually seen in conditions marked by hormonal disturbances, like diabetes, menopause, or thyroid dysfunction. Hormones work to regulate blood sugar and growth, so chemical changes in metabolic reactions like fat storage can lead to excessive weight gain or sudden losses.

Regarding hormones and anxiety,[5] dopamine is a prominent neurohormone to monitor closely. It is linked to reward and motivation and is often dysregulated when there is an anxiety disorder[6] in place. 

Which Hormones Cause Anxiety?

Stress Hormones

Changes in stress hormones[7] can cause anxiety due to alterations in the brain. As previously mentioned, stress hormones are part of the fight or flight cascade when the body detects threats. However, chronic stress and unbalanced hormones may cause the body to overreact.

Abnormal cortisol levels, a primary stress hormone, often underscore hormonal anxiety.[8] When there is constant exposure to cortisol, the efficiency of various bodily functions is interrupted, increasing the risk of anxiety, mood disorders, weight gain, and sleep disturbances. 

Sex Hormones

The highs and lows of sex hormones, like testosterone and estradiol, over your lifespan, can also affect anxiety. Elevated levels promote brain plasticity and can alter intracellular signaling in the brain. Unfortunately, this neural plasticity also impacts what your body learns during high-stress situations, and as a result, stressful events can raise the likelihood of developing anxiety disorders.

Men are prone to experience increased or decreased testosterone levels, resulting in hormone-related anxiety, especially in erectile dysfunction or fertility troubles. However, hormonal anxiety is more commonly seen in women[9] due to changes across the life cycle, such as menstruation, pregnancy, and menopause.  

You may wonder what hormones cause anxiety before a period, and the answer is progesterone and estradiol. These hormones are elevated in the luteal phase of a cycle 14 days before menstruation begins. Intense emotions, mood swings, and anxious feelings often characterize the luteal phase. Additionally, insulin use is altered during pregnancy, and oxytocin is released, which can contribute to heightened anxiety and irritable mood.

Estrogen levels, on the other hand, can be tricky because the pendulum of menstruation, pregnancy, and menopause can make it difficult to achieve optimal balance. But can too much estrogen cause anxiety? The answer depends on the individual’s reproductive stage and how dominant estrogen is compared to progesterone.

High estrogen levels can be protective against emotional disturbances, but if your estrogen far exceeds your progesterone levels, it can lead to low mood and anxiety. However, if an individual is going through menopause, low estrogen can cause anxiety,[10] mood swings, hot flashes, and disturbed sleep.

Thyroid Hormones

Issues with thyroid hormones[11] can result in anxiety, as well as feelings of fatigue and irritability. Hyperthyroidism, in which the thyroid is overactive, may contribute to the onset of anxiety and nervousness. Alternatively, hypothyroidism or an underactive thyroid may be linked to depression and fatigue.

Thyroid disease can be characterized by common hormone imbalance manifestations, like weight gain and menstrual changes. 

How Can I Stop Hormonal Anxiety?

One way to alleviate hormone-related anxiety is through hormone replacement therapy. This is most often effective with thyroid dysfunction, as medicines can replace the missing hormones, thus reducing anxiety and mood disorders. Some research studies[12] have shown that taking synthetic or natural hormones to restore sex hormones during menopause can be beneficial for reducing depression and anxiety symptoms.

Additionally, cognitive behavioral therapy can be another effective option. Some might consider online therapy because it provides convenient resources in a safe, private setting. Certain platforms allow you to match with a therapist based on faith and specialty to best meet your personalized therapy needs. 

Tips To Support Balanced Hormones & Reduce Anxiety

Counseling And Networking

can hormones cause anxiety
Woman seeking help with anxiety through counseling.

In some cases, individuals diagnosed with hormonal anxiety may have already exhibited signs of generalized anxiety disorder, even before hormonal imbalances contributed to their condition. Therefore, it may help to log your thoughts and feelings in a journal. And when you’re ready, you may want to consider meeting with a counselor, seeking online therapy, or joining a support group. 

Meditation

can hormones cause anxiety
Woman meditating to help ease anxiety.

Furthermore, discussing your feelings and journaling can be a smooth transition into meditation and mindfulness activities. Addressing your fears and improving your concentration can help you overcome the hurdle of a blank mind or irrational thoughts. Increased engagement with your daily tasks can also help reduce your preoccupation with fear and worry. 

Exercise

can hormones cause anxiety
Woman doing yoga to clear her mind and reduce stress.

Yoga can be an effective and practical activity to include in your mindfulness efforts. Spend time meditating and stretching your body, as this can adequately restore your body and mind. 

You can also increase the intensity of your exercise by going for walks or doing cardio. Weight maintenance helps protect against obesity, often linked to anxiety and low mood. According to the Physical Activity Guidelines for Americans,[13] the average healthy adult should aim for at least 150 minutes of moderate-intensity weekly activity.

Diet

can hormones cause anxiety
Eating a nutrient-dense diet can help ease anxiety symptoms.

Meeting our nutrition needs is essential as many nutrients supply neurotransmitters with the necessary components for adequate function. Including herbs, spices, and various fruits and vegetables in your healthy diet can provide anti-inflammatory nutrients and antioxidants that support hormonal balance. 

For example, you can increase your intake of the nutrient vitamin D through sources like salmon to help control your dopamine levels. Additionally, you can increase your magnesium intake through sources like chia seeds and spinach to help calm the nervous system and prompt relaxation.

Sleep

can hormones cause anxiety
Woman getting enough sleep to balance hormones and reduce anxiety.

Regarding sleep and hormone fluctuations, the main goal is to reset your circadian rhythm in order to balance your cortisol during the day and melatonin at night. It may help to set a consistent bedtime and sleep in a dark room. Try to avoid screen time a few hours before bed. Instead, consider engaging in relaxation exercises to reduce restlessness before sleeping.

Final Thought

Proper sleep, eating habits, and exercise can support the brain and help modulate hormones like insulin or dopamine. This can alleviate anxiety and reduce common comorbidities like weight issues and fatigue. Making healthy connections between your brain chemistry and body can help you find balance in your life and anxiety management!


+ 13 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Cleveland Clinic. (2022). Hormonal Imbalance: Causes, Symptoms & Treatment. [online] Available at: https://my.clevelandclinic.org/health/diseases/22673-hormonal-imbalance
  2. Mittal, R., Debs, L.H., Patel, A.R., Nguyen, D., Patel, K.S., O’Connor, G., M’hamed Grati, Mittal, J., Yan, D., Eshraghi, A.A., Deo, S.K., Daunert, S. and Liu, X. (2017). Neurotransmitters: The Critical Modulators Regulating Gut–Brain Axis. [online] 232(9), pp.2359–2372. doi:https://doi.org/10.1002/jcp.25518.
  3. Mayo Clinic. (2017). Generalized anxiety disorder – Symptoms and causes. [online] Available at: https://www.mayoclinic.org/diseases-conditions/generalized-anxiety-disorder/symptoms-causes/syc-20360803
  4. Roop, J. (2018). HORMONE IMBALANCE-A CAUSE FOR CONCERN IN WOMEN. [online] doi:https://doi.org/10.26479/2018.0402.18.
  5. Cleveland Clinic. (2022). Dopamine: What It Is, Function & Symptoms. [online] Available at: https://my.clevelandclinic.org/health/articles/22581-dopamine
  6. Calipari, E.S. (2020). Dopamine Release in the Midbrain Promotes Anxiety. [online] doi:https://doi.org/10.1016/j.biopsych.2020.08.016.
  7. Merz, C.J. and Wolf, O.T. (2022). How stress hormones shape memories of fear and anxiety in humans. Neuroscience & Biobehavioral Reviews, 142, p.104901. doi:https://doi.org/10.1016/j.neubiorev.2022.104901.
  8. Mayo Clinic. (2021). Chronic stress puts your health at risk. [online] Available at: https://www.mayoclinic.org/healthy-lifestyle/stress-management/in-depth/stress/art-20046037
  9. National Institute of Mental Health (NIMH). (2017). Generalized Anxiety Disorder. [online] Available at: https://www.nimh.nih.gov/health/statistics/generalized-anxiety-disorder
  10. Brain (2019). Can Menopause Cause Anxiety, Depression or Panic Attacks? [online] Cleveland Clinic. Available at: https://health.clevelandclinic.org/is-menopause-causing-your-mood-swings-depression-or-anxiety/
  11. Mayo Clinic. (2022). Thyroid disease: How does it affect your mood? [online] Available at: https://www.mayoclinic.org/diseases-conditions/hyperthyroidism/expert-answers/thyroid-disease/faq-20058228
  12. Gordon, J., Rubinow, D.R., Eisenlohr-Moul, T.A., Xia, K., Schmidt, P. and Girdler, S.S. (2018). Efficacy of Transdermal Estradiol and Micronized Progesterone in the Prevention of Depressive Symptoms in the Menopause Transition. [online] 75(2), pp.149–149. doi:https://doi.org/10.1001/jamapsychiatry.2017.3998.
  13. U.S. Department of Health and Human Services (2018). Physical Activity Guidelines for Americans 2nd edition. [online] health.gov. Available at: https://health.gov/sites/default/files/2019-09/Physical_Activity_Guidelines_2nd_edition.pdf.
Christine VanDoren

Medically reviewed by:

Chelsea Rae Bourgeois

Christine is a certified personal trainer and nutritionist with an undergraduate degree from Missouri State University. Her passion is helping others learn how strong and healthy they can become by transforming their daily habits. Christine spends most of her time in the gym, hiking, painting, and learning how she can influence others through positivity!

Medically reviewed by:

Chelsea Rae Bourgeois

Journal of Physical Education and Sport

Trusted Source

Go to source

SciELO - Scientific Electronic Library Online

Trusted Source

Go to source

African Journals Online

Non-profit Platform for African Journals

Trusted Source
Go to source

Journal of The American Board of Family Medicine

American Board of Family Medicine

Trusted Source
Go to source

Informit

RMIT University Library

Trusted Source
Go to source

European Food Safety Authority

Science, Safe food, Sustainability

Trusted Source
Go to source

OrthoInfo

American Academy of Orthopaedic Surgeons

Trusted Source
Go to source

American Academy of Family Physicians

Strengthen family physicians and the communities they care for

Trusted Source
Go to source

Agricultural Research Service

U.S. Department of Agriculture

Trusted Source
Go to source

The American Journal of Medicine

Official Journal of The Alliance for Academic Internal Medicine

Trusted Source
Go to source

National Institute on Alcohol Abuse and Alcoholism

Database From National Institute Of Health

Trusted Source
Go to source

Lippincott Journals

Subsidiaries of Wolters Kluwer Health, Inc.

Trusted Source
Go to source

National Institute on Aging

Database From National Institute Of Health

Trusted Source
Go to source

Translational Research

The Journal of Laboratory and Clinical Medicine

Trusted Source
Go to source

Cell

An All-science Publisher

Trusted Source
Go to source

Journal of Translational Medicine

BioMed Central

Part of Springer Nature
Go to source

Federal Trade Commission

Protecting America's Consumers

Trusted Source
Go to source

National Human Genome Research Institute

Database From National Institute Of Health

Trusted Source
Go to source

Food Production, Processing and Nutrition

BioMed Central

Part of Springer Nature
Go to source

BMC Gastroenterology

BioMed Central

Part of Springer Nature
Go to source

ACS Publications

A Division of The American Chemical Society

Trusted Source
Go to source

Annual Reviews

Independent, Non-profit Academic Publishing Company

Trusted Source
Go to source

PubChem

National Center for Biotechnology Information

National Library of Medicine
Go to source

PLOS Journals

Nonprofit Publisher of Open-access Journals

Trusted Source
Go to source

Thieme E-books & E-Journals

Peer-reviewed & Open Access Journal

Trusted Source
Go to source

European Journal of Agriculture and Food Sciences

Peer-reviewed International Journal Publishes

Trusted Source
Go to source

Royal Society of Chemistry Publishing Home

Chemical Science Journals, Books and Database

Trusted Source
Go to source

Frontiers

Publisher of Peer-reviewed Articles in Open Acess Journals

Trusted Source
Go to source

De Gruyter

German Scholarly Publishing House

Trusted Source
Go to source

Hindawi

Open Access Research Journals & Papers

Trusted Source
Go to source

Oilseeds and Fats, Crops and Lipids

EDP Sciences

Trusted Source
Go to source

Cambridge Core

Cambridge University Press

Trusted Source
Go to source

FoodData Central

U.S. Department Of Agriculture

Trusted Source
Go to source

Journal of the American Heart Association

Peer-reviewed Open Access Scientific Journal

Trusted Source
Go to source

National Center for Complementary and Integrative Health

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

The Americans with Disabilities Act

U.S. Department of Justice Civil Rights Division

Trusted Source
Go to source

Journal of the Academy of Nutrition and Dietetics

Organization of Food and Nutrition Professionals

tr
Go to source

Sage Journals

Database From Sage Publications

Trusted Source
Go to source

National Institute of Drug Abuse

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

The ClinMed International Library

A Repository and an Open Access Publisher for Medical Research

Trusted Source
Go to source

The Royal Society Publishing

United Kingdom's National Academy of Sciences

Trusted Source
Go to source

APA PsycNet

Database From American Psychological Association

Trusted Source
Go to source

The Pharma Innovation Journal

Peer-reviewed And Refereed Journal

Trusted Source
Go to source

Asian Journal of Pharmaceutical Research and Development

Peer-reviewed Bimonthly Journal

Trusted Source
Go to source

British Pharmacological Society

Journals - Wiley Online Library

Trusted Source
Go to source

American Psychological Association

Scientific and Professional Organization of Psychologists

Trusted Source
Go to source

AAP Publications

Database From American Academy of Pediatrics

Trusted Source
Go to source

Karger Publishers

Academic Publisher of Scientific and Medical Journals and Books

Trusted Source
Go to source

Cambridge University Press & Assessment

Database From Cambridge University

Trusted Source
Go to source

National Institute of Mental Health

Database From National Institute Of Health

U.S. Department of Health and Human Services
Go to source

MDPI

Publisher of Open Access Journals

Trusted Source
Go to source

Bulletin of the National Research Centre

Part of Springer Nature

Trusted Source
Go to source

The New England Journal of Medicine

Massachusetts Medical Society

Trusted Source
Go to source

Economic Research Service

U.S. DEPARTMENT OF AGRICULTURE

Trusted Source
Go to source

MedlinePlus

Database From National Library of Medicine

U.S Department of Health and Human Services
Go to source

National Institute of Health

An agency of the U.S. Department of Health and Human Services

Trusted Source
Go to source

Trusted Source

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

The BMJ

Weekly Peer-reviewed Medical Trade Journal

The British Medical Association
Go to source

The British Psychological Society

The British Psychological Society is a charity registered in England

Database From Wiley Online Library
Go to source

National Heart, Lung, and Blood Institute

Database From National Institute Of Health

U.S Department of Health and Human Services
Go to source

PubMed

Database From National Institute Of Health

U.S National Library of Medicine
Go to source

DailyMed

Database From National Institute Of Health

U.S National Library of Medicine
Go to source

Google Scholar

Go to source

Science.gov: USA.gov for Science

Government Science Portal

Go to source

ResearchGate

Social Network Service For Scientists

Find and share research
Go to source

American Heart Association

To be a rentless force for a world of longer, healthier lives

Go to source

BioMed Central

Research in progress

Go to source

JAMA Network

Home of JAMA and the Specialty Journals of the American Medical Association

Go to source

Springer Link

Database From Springer Nature Switzerland AG

Springer - International Publisher Science, Technology, Medicine
Go to source

ODS

Database from Office of Dietary Supplements

National Institutes of Health
Go to source

Federal Trade Commission

Bureaus of Consumer Protection, Competition and Economics
Go to source

Trusted Source

Database From U.S. Department of Health & Human Services

Governmental Authority
Go to source

Oxford Academic Journals

Oxford University Press

Trusted Source
Go to source

Taylor & Francis Online

Peer-reviewed Journals

Academic Publishing Division of Informa PLC
Go to source

WHO

Database from World Health Organization

Go to source

Journal of Neurology

Peer-reviewed Medical Journal

American Academy of Neurology Journal
Go to source

ScienceDirect

Bibliographic Database of Scientific and Medical Publications

Dutch publisher Elsevier
Go to source

Wiley Online Library

American Multinational Publishing Company

Trusted Source
Go to source

Centers for Disease Control and Prevention

U.S. National Public Health Agency

U.S Department of Health and Human Services
Go to source

Trusted Source

Database from U.S. National Library of Medicine

U.S. Federal Government
Go to source

U.S. Food & Drug Administration

Federal Agency

U.S Department of Health and Human Services
Go to source

PubMed Central

Database From National Institute Of Health

U.S National Library of Medicine
Go to source
Feedback

Help us rate this article

Thank you for your feedback

Keep in touch to see our improvement