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Best CBD Gummies For Sleep 2024: Top Choices That Support Insomnia

Kate Barrington

Updated on - Written by
Medically reviewed by Kathy Shattler, MS, RDN

All articles are produced independently. When you click our links for purchasing products, we earn an affiliate commission. Learn more about how we earn revenue by reading our advertise disclaimer.

CBDfx CBD Gummies for Sleep with Melatonin

CBDfx CBD Gummies for Sleep with Melatonin

  • Contains 50 milligrams of CBD per serving. 
  • USA-made, vegan, and gluten-free.
  • Made from organic hemp. 
  • Contains melatonin and magnesium.

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CBDistillery Broad Spectrum CBD Sleep Gummies

CBDistillery Broad Spectrum CBD Sleep Gummies + Melatonin

  • Sugar-coated and flavored with mixed berries.
  • Formulated with CBD, hemp extract, and melatonin. 
  • Third-party tested.

15% Off Coupon: HEALTHCANAL15

Exhale Wellness CBD + CBN Sleep Gummies

Exhale Wellness CBD + CBN Sleep Gummies

  • Contains 10 milligrams of CBN per gummy.
  • Natural assorted fruit flavor. 
  • Made with non-GMO and organic natural ingredients.

20% Off Coupon: HEALTHCANAL

Your requirements for sleep change as you get older, but many people struggle to get the sleep they need. According to the National Institutes of Health, as many as 1 in 3 American adults[1] don’t regularly get enough sleep for optimal health and wellness. That’s an estimated 50 to 70 million people. 

The Internet is full of tips and tricks for getting more or better sleep, from mindfulness meditation[2] to cultivating better sleep hygiene. When you just need a little help to complement your other efforts, CBD gummies for sleep are an option to consider.  

While CBD oil can be tricky to dose properly, gummies are ready-made and easy to take right before bed. We’ve compared dozens of brands to find the best CBD gummies for sleep based on potency, purity, safety, and other key factors. Read on for detailed reviews of the top 10 CBD gummy brands to help you sleep better at night.

Best CBD Gummies For Sleep And Anxiety On The Market In (July. 2024)

Is It Safe To Use CBD For Sleep?

Many prescription sedatives[3] come with a high risk for dependence, but CBD-infused gummies offer a low-risk alternative as a natural sleep aid. 

CBD is a naturally occurring, non-impairing compound derived from hemp. Though all supplements have the potential to cause side effects, negative effects[4] linked to CBD tend to be mild. Some of the most commonly reported side effects include dry mouth, fatigue, reduced appetite, and diarrhea. While CBD edibles are generally considered safe and may help you fall asleep, the FDA cautions against[5] combining them with other products that slow brain activity, such as alcohol or sleeping pills. If you choose to take CBD for sleep, follow dosing recommendations closely, reduce your dosage, or discontinue use if you experience negative effects.

Best CBD Gummies For Sleep And Anxiety In 2024

CBDfx CBD Gummies For Sleep With Melatonin 

CBDfx CBD Gummies for Sleep with Melatonin

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See CBDfx Reviews

Formulated with 50 milligrams of CBD and 5 milligrams of melatonin per serving; these broad-spectrum CBD gummies act as a gentle, natural sleep aid.

  • Contains 50 milligrams of CBD per serving. 
  • USA-made, vegan, and gluten-free.
  • Made from organic hemp. 
  • Contains melatonin and magnesium.
  • Sweetened with organic cane sugar.
  • The flavor may not be appealing to some.

While some evidence[6] suggests that the combination of CBD and THC may be more effective than CBD alone for certain applications, it’s understandable if you prefer CBD-only gummies. If you’re looking for broad-spectrum gummies for sleep support, this CBDfx formula may be right for you. It contains a gentle dose of 50 milligrams of THC-free CBD per serving with 5 milligrams of melatonin and 10 mg of magnesium. 

This CBDfx formula is our top pick for the overall best CBD gummies. All CBDfx formulas are cruelty-free and made in the USA. Their CBD products are made with all-natural ingredients, including organic hemp. These gummies are free from genetically modified organisms or GMOs, and all formulas are tested by independent, third-party labs for purity, potency, and safety. 

Lightly sweetened with organic cane sugar, these gummies are enriched with natural botanicals like passion flower, chamomile, and lemon balm to help promote calmness.[7]

CBDistillery Broad Spectrum CBD Sleep Gummies + Melatonin

CBDistillery Broad Spectrum CBD Sleep Gummies

15% Off Coupon: HEALTHCANAL15

See CBDistillery Reviews

If the flavor of CBD oil turns you off, these mixed berry CBD gummies might be more appealing. 

  • Sugar-coated and flavored with mixed berries.
  • Formulated with CBD, hemp extract, and melatonin. 
  • Third-party tested for major contaminants.
  • More expensive than some CBD brands.
  • Includes 2 grams of sugar per gummy.

These sweet-tasting gummies are full of berry flavor and lightly coated in sugar, so they go down easy. Each serving contains 38 milligrams of broad-spectrum hemp extract, 30 mg of CBD, and a hint of melatonin[8] to help you fall asleep naturally. 

To verify the purity and potency of their products, CBDistillery offers full lab results online. Every product is tested by an independent, third-party lab. Their gummies are also U.S. Hemp Authority Certified, and their farmers follow natural farming practices. 

Though you may pay a lower retail price for gummies from another CBD company, CBDistillery offers exceptional value with its subscribe & save program. Save 30% and receive free shipping – on top of the standard 60-day satisfaction guarantee – when you select auto-ship.

Exhale Wellness CBD + CBN Sleep Gummies

Exhale Wellness CBD + CBN Sleep Gummies

20% Off Coupon: HEALTHCANAL

See Exhale Wellness Reviews

Enjoy the sleep-promoting benefits of numerous cannabinoid compounds with these Exhale CBD gummies enriched with cannabinol or CBN.

  • Supplemented with 10 mg of CBN per gummy.
  • Natural assorted fruit flavor. 
  • Made with non-GMO and organic natural ingredients.
  • More expensive than many CBD brands.
  • Delivery may not be available to all states.

Cannabinol or CBN is just one of the hundreds of cannabinoid compounds derived from the hemp plant and it isn’t the only one that can help you achieve quality sleep. Limited research[9] suggests that CBN, which is mildly psychoactive, may offer sleep-promoting benefits as well. 

In addition to 25 milligrams of CBD per gummy, this Exhale formula contains 10 milligrams of CBN and 5 milligrams of melatonin. These gummies are made with all-natural, non-GMO, and organic ingredients. They’re free from artificial sweeteners, and they are naturally flavored. 

Like other reputable CBD companies, Exhale has all its products tested by third-party labs, and you can view the test results on its website. Exhale products are expensive in comparison to other brands, but they offer a wider array of formulations than many companies.

Joy Organics CBD Gummies For Sleep

Joy Organics CBD Gummies for Sleep

Check Price

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See Joy Organics Reviews

Only the top CBD gummies are verified for purity and potency by third-party labs. All Joy Organics gummies are, so you can be sure of what you’re buying. 

  • All products are tested by ISO-accredited laboratories.
  • Made with non-GMO, USA-grown hemp. 
  • Vegan-friendly and gluten-free.
  • THC presence may result in a positive drug screening.
  • Delivery may not be available in all states.

Buying CBD gummies can be expensive, so you want to be sure of what you’re getting. Reputable brands have their products tested by independent labs to verify their purity and potency – brands like Joy Organics. All products are tested by International Organization for Standardization or ISO-accredited labs and each product label carries a QR code you can scan to view the test results. 

Joy Organics gummies are made with non-GMO, USA-grown hemp. This formula is made with full-spectrum hemp distillate and each gummy contains the following: 30 milligrams of CBD, 3 milligrams of CBN, 1 milligram of THC, and 3 milligrams of melatonin. These gummies are vegan, gluten-free, and naturally flavored with berry.

Royal CBD

Royal CBD Gummies

20% Off Coupon: HC20

See Royal CBD Reviews

Royal CBD gummies for sleep are made from CBD isolate with no trace of THC. It is all-natural made from hemp, and free from herbicides and other chemicals. The Royal CBD edibles are third-party tested for quality.

  • Use CO2 extraction
  • Pesticide-free and locally-grown American hemp
  • Three tasteful flavors
  • No gluten or GMO ingredients
  • Contain no tetrahydrocannabinol (THC).
  • Reasonable price
  • You can only purchase Royal CBD online.

Royal CBD is an American company that only uses the cleanest hemp to make its CBD isolates. The reports show no traces of synthetic additives or genetically modified organisms, GMOs.

These sleep gummies are put through rigorous third-party testing to ensure they are what they claim to be. They’re also gluten-free and vegan-friendly.

These CBD gummies are isolates meaning they do not contain THC, the psychoactive ingredient. This means that you do not get the high THC induced. These isolates contain only CBD minus cannabinoids and other elements like flavonoids and terpenes.

Royal CBD users can get the gummies in two dosages: 10 and 25 mg.

These organic CBD gummies are also a bit expensive, but that is not a surprise since they are all-natural, and the brand offers premium CBD gummies

FOCL CBD + CBN Sleep Gummies

FOCL CBD + CBN Sleep Gummies

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See FOCL Reviews

It’s important to choose CBD gummies made with quality ingredients. These FOCL sleep gummies are vegan, non-GMO, and made with organic ingredients.

  • Made in the USA with organic ingredients.
  • Choose from broad-spectrum or full-spectrum. 
  • Save $10 when you purchase a 3-pack.
  • Delivery may not be available to all states.
  • Each gummy contains 2.5 grams of sugar.

FOCL gummies are made in the USA with organic ingredients. This formula is gluten-free, cruelty-free, and vegan-friendly. Each gummy contains 25 milligrams of CBD plus 15 milligrams of CBN, 50 mg of L-theanine, and 25 mg of passion flower extract. What makes these gummies unique is that they also contain L-theanine – about 50 milligrams per gummy. L-theanine is a naturally occurring amino acid with proven sleep-promotion benefits.[10] Studies show that L-theanine improves sleep disturbances and may be complementary to the effects of CBD, CBN, and passion flower. 

Not only does FOCL offer a great deal of variety with their CBD products, but they offer exceptional value. You can save $10 by purchasing CBD gummies in a 3-pack or save 20% on your order when you start a subscription.

Green Roads Sleepy Zs CBD, CBN Gummies

15% Off Coupon: HEALTHCANAL

See Green Roads Reviews

When you don’t want to commit to a full month’s supply of a CBD product, a brand like Green Roads that offers 10-count packs of gummies might be the right choice. 

  • Choose from 30-count or 10-count packs.
  • Vegan and gluten-free. 
  • Supplemented with 5 milligrams of melatonin.
  • Per-gummy price is higher for 10-count.
  • Each gummy has 2 grams of sugar.

While CBD is generally regarded as safe, every person’s body responds to supplements differently. If you’re looking for a brand that enables you to try a CBD product without committing to a full month’s worth, consider Green Roads. 

Green Roads Sleepy Zs gummies are available in 30- and 10-count packs. Each gummy contains 22.5 milligrams of CBD and 2.5 milligrams of CBN plus 5 milligrams of melatonin. These are broad-spectrum, so they do not contain THC. 

While all the gummies have some form of sugar in them, it is wise to remember that sugar accumulates in the diet and is bad for dental health. Be sure to use good dental hygiene when consuming sugar-laden gummies that can stick to your teeth and promote dental caries.

Medterra True Full Spectrum Deep Sleep CBD Gummies

Medterra True Full Spectrum Deep Sleep CBD Gummies

15% Off Coupon: HEALTHCANAL

See Medterra Reviews

If you’re seeking deeper and more restorative sleep then you might want to think about adding THC to your CBD gummy.

  • Made in the USA from full-spectrum organic hemp.
  • Contains 3 mg of melatonin.
  • The tasty mixed berry flavor is available in 30 and 60-count packs.
  • THC may result in a positive drug screening. 
  • Delivery may not be available to all states.

Medterra CBD products are available in a wide range of dosages and forms. From full-spectrum CBD oils to topicals and gummies, you have plenty to choose from. They make it easy to find what you’re looking for by categorizing their CBD products by type and benefit. 

When it comes to sleep support, Medterra’s True Full Spectrum Deep Sleep gummies are an excellent choice. They come in a tasty mixed berry flavor and contain 25 milligrams of CBD with 3 milligrams of melatonin and 2 mg THC per gummy. The thing to keep in mind with this option is that they are full-spectrum CBD gummies which means they may contain THC – about 2 milligrams per gummy. This could be a good thing, however, if you suffer from anxiety as some studies[11] have linked THC supplementation with reduced symptoms of anxiety. If you’re looking for CBD gummies for sleep and anxiety, this could be a good option.

Charlotte’s Web CBD For Sleep Gummies

Charlotte's Web CBD For Sleep Gummies

20% Off Coupon: HEALTHCANAL

See Charlotte’s Web Reviews

When you just need a little bit of help getting to sleep, these low-dose gummies from Charlotte’s Web might be the perfect fit.

  • A low dose of 10 milligrams of CBD per gummy.
  • Contains 3 mg of melatonin.
  • Made with USA-grown hemp.
  • May contain trace amounts of THC.
  • Contains 3 grams of added sugar.

Many CBD companies make higher-dosage gummies with 20 to 50 milligrams of CBD per serving but Charlotte’s Web offers low-dose gummies for when you need just a little bit of sleep support. These raspberry-flavored gummies contain 10 milligrams of CBD, 3 mg of melatonin, and 20 mg of full-spectrum hemp extract per gummy and they are sold in 30-, 60-, and 90-count containers. 

They’re made from all-natural ingredients including USA-grown hemp. Because they’re lower in dosage than other brands, Charlotte’s Web gummies are also less expensive. However, a serving size is two gummies, not one such as with other products.

You can save 20% on your order when you start a subscription.

Koi CBD Gummies Nighttime Rest

Koi CBD Gummies Nighttime Rest

15% Off Coupon: HEALTHCANAL

See Koi CBD Reviews

When you need a simple broad-spectrum gummy, Koi has you covered. Choose from a 6-, 20-, or 60-count container.

  • Made with broad-spectrum CBD.
  • Contains 10 mg CBD and 2.5 mg melatonin per gummy.
  • The dosage may be too low for some.
  • Fairly expensive per gummy.
  • Contains 4 grams of added sugars per serving.

If you prefer not to consume THC, a broad-spectrum formulation is for you. These Koi gummies are made with Koi PRIZM Broad Spectrum CBD and contain 10 mg CBD and an added 2.5 milligrams of melatonin per gummy. The serving size is two gummies. The formula is made from USA-grown hemp and they’re naturally sweetened with tapioca syrup and cane sugar. 

Not only are Koi gummies made with high-quality ingredients, but they’re deliciously flavored like cherry limeade. Choose from a 6-, 20-, or 60-count container and save up to 20% when you start a subscription.

JustCBD Gummies For Sleep

JustCBD Gummies For Sleep

15% Off Coupon: HEALTHCANAL

JustCBD products come in a wide range of dosages but few companies offer gummies in bulk. JustCBD gummies, however, are available in containers ranging from 250 milligrams to 3,000 milligrams of CBD.

  • Containers of up to 220 gummies.
  • Each jar contains an assortment of flavors.
  • Third-party lab tested for cannabinoid profile.
  • Contains artificial flavors and colors.
  • Contains 6 grams of sugar per serving.

When you first start taking CBD for sleep, it’s important to start with a low dose and slowly increase it until you find what works for you. Once you do, you can start purchasing gummies in bulk so you can easily achieve your ideal dosage. With dosages ranging from 10 milligrams to 13 milligrams of CBD per gummy, JustCBD gummies make it easy to customize your dosage. Plus, they offer containers of up to 220 gummies so you won’t run out. 

JustCBD gummies are made with a potent blend of CBD oil and 8 mg of melatonin to encourage healthy sleep. Each jar contains a wide variety of flavors including cherry, watermelon, orange, blue raspberry, and grape. Recommended serving sizes are two to four gummies.

Make a one-time purchase or save 30% when you select Autoship.

PlusCBD Sleep Gummies

PlusCBD Sleep Gummies

15% Off Coupon: healthcanal

CV Science, the company behind PlusCBD, was one of the first to investigate CBD as a potential treatment for various ailments. Aside from the gummies, they have various other CBD products in their line.

  • Organic, non-GMO hemp
  • CO2 extraction
  • Broad spectrum CBD
  • Quality and safety have been verified in the lab
  • Not vegan-friendly

The PlusCBD oil gummies come in three versions. They are; Regular, Calm, and Sleep. Each of these versions contains ten milligrams of full-spectrum CBD. The Calm has extra ingredients like L-theanine[12] and 5-HTP. Then Sleep has magnolia, melatonin, and lemon balm.

These gummies are further categorized into four delicious flavors, namely:

  • Delicious raspberry flavor. Strawberry lemonade.
  • Citrus punch.
  • Cherry mango.

On the flip side, these CBD-infused PlusCBD gummies are not vegan-friendly since they have gelatin. On that note, they miss quite a large chunk of vegan clients who would benefit from CBD sleep gummies

How Does CBD Work For Sleep?

While CBD is not a sedative, it benefits the mind and body in numerous ways, which may help you get to sleep faster and improve your sleep quality. 

The benefits of CBD gummies for sleep vary from person to person, largely depending on the underlying factors affecting the individual’s frequency and severity of sleep deprivation. Common causes for poor sleep may include sleep disorders like insomnia as well as chronic stress, physical pain, anxiety, depression, and various medical conditions. 

Interestingly, CBD has been shown to benefit many, if not all, of these areas. 

Numerous studies[13] have shown a link between sleep and pain. Not only can sleep disturbance contribute to the development of chronic pain, but pain can keep you from getting a good night’s sleep. A 2022 literature review[14] concluded that CBD might be a safe alternative to opioids and other analgesic agents for pain management. 

In a 2020 study[15] using animal models, CBD was identified as an anxiolytic compound that calmed down the brain and nervous system without negatively impacting consciousness. In human clinical trials,[16] CBD was shown to help with anxiety as well as other mental health conditions such as schizophrenia and depression. 

Cannabinoid compounds have also demonstrated antioxidant activity[17] – which may help relieve complications related to oxidative stress – and anti-inflammatory benefits, which render it a possible treatment for a variety of diseases, including anxiety, cardiovascular disease, epilepsy, and neurodegenerative disease. 

By acting on the factors that make it harder to fall asleep or stay asleep, CBD gummies may help you achieve more restorative sleep regularly.

Pros And Cons

It has become increasingly popular for people to take CBD oils for sleep but dosing liquids can be tricky. The primary benefit of a CBD gummy over an oil is that you can simply pop it into your mouth and be done with it. Gummies are available in a wide range of dosages which makes it easy to customize your routine and you can find them in a variety of flavors as well. 

Though there are many benefits to taking CBD gummies, there are some things to be aware of. First and foremost, remember that supplements like CBD products are not regulated by the FDA. It’s important to shop smart to ensure the product you choose is made safely from quality ingredients. 

Second, remember that CBD gummies shouldn’t be taken with other sedatives like sleeping pills. You would also be wise to consult your physician before taking them to make sure they won’t interact with any medications you might already be taking.

What To Look For When Buying CBD Gummies For Sleep

When purchasing any kind of supplement it’s essential to prioritize your safety. Whether you’re shopping for full-spectrum CBD gummies, CBD isolate, or other hemp-derived CBD products, start by looking for reputable brands. Visit the Better Business Bureau, look at product reviews, or run a Whois search to determine a company’s reputation. 

Look for brands that use USA-grown hemp and check that the company lists their supplier on their website. Check what kind of CBD the product contains and how much of it – most products will list the CBD content per gummy and container. 

If you’re not purchasing a pure CBD product like CBD isolate, read the label to find out what other ingredients the product contains. Many people prefer to avoid artificial sweeteners and synthetic colors or flavors. If you have dietary restrictions, check for common allergens. 

Finally, check to make sure the product has been tested for purity and potency by an independent, third-party laboratory. The company should post the results of these tests on their website or have a QR code on the product label you can scan.

How To Use CBD Gummies For Sleep

Taking a CBD gummy for sleep is incredibly simple. Start by choosing a product that suits your needs for dosage, taking into account your preferences for flavor and synergistic ingredients such as other cannabinoids or melatonin. If you’re not sure whether you’re going to like using CBD products, try a brand that offers low-count packages. 

To use CBD gummies, simply take the gummy about 30 to 60 minutes before you go to bed. It’s important to chew the product thoroughly to make sure your body absorbs CBD. And, be sure to brush your teeth after consuming sugar-laden gummies.

Recommended Dosage

When it comes to CBD products, there is no clinically recommended dosage. It’s best to start with a low dose and increase over time until you experience the desired effect. 

Keep in mind that different products may contain more than just CBD. Full-spectrum CBD gummies, for example, may contain THC while products made with CBD isolate or are broad-spectrum will not. 

Final Thought

Before taking CBD products, it is important to realize that while CBD is generally regarded as safe, products are not closely regulated by the FDA. 

It’s wise to consult a qualified medical professional before taking CBD and to choose a reputable brand. Follow dosing recommendations closely and keep an eye out for side effects. If you experience negative effects, reduce your dosage or discontinue use.

Frequently Asked Questions

When should I consume CBD gummies before going to bed?

Because gummies take longer to absorb than CBD oil, it’s best to consume them about 30 to 60 minutes before bed to ensure restful sleep.

Do CBD gummies contain THC?

Sometimes. You can purchase CBD gummies with or without THC. If the product is labeled full spectrum, it contains cannabinoid compounds other than CBD, including up to a 0.3% concentration of THC. Broad-spectrum gummies do not contain THC.

Will CBD gummies make me tired the following day?

No. Because CBD is not a sedative, it should not make you feel tired the day after you take it.

Do CBD gummies for sleep cause intoxication?

No. Cannabidiol is a non-intoxicating compound derived from hemp. It does not have psychoactive properties like THC which is derived from the cannabis plant. And, THC at legal concentrations of less than 0.3% is not psychoactive but may show up in a drug test.

How many CBD gummies should you take before going to bed?

It depends on the dosage. There are no clinical dosing recommendations for CBD, so it may be best to start with a low dose and increase over time until you experience the desired effect.

Will CBD gummies be detected in a drug test?

No. Drug tests do not typically screen for CBD. If you are taking CBD gummies that contain THC, however, that could result in a positive drug test.


+ 17 sources

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. NHLBI, NIH. (2021). Sleep Health. [online] Available at: https://www.nhlbi.nih.gov/health-topics/education-and-awareness/sleep-health
  2. ‌Rusch, H.L., Michael Del Rosario, Levison, L.M., Olivera, A., Livingston, W.S., Wu, T. and Gill, J. (2018). The effect of mindfulness meditation on sleep quality: a systematic review and meta‐analysis of randomized controlled trials. Annals of the New York Academy of Sciences, [online] 1445(1), pp.5–16. doi:https://doi.org/10.1111/nyas.13996.
  3. ‌Weaver, M.F. (2015). Prescription Sedative Misuse and Abuse. The Yale journal of biology and medicine, [online] 88(3), pp.247–56. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553644/
  4. ‌Iffland, K. and Franjo Grotenhermen (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and cannabinoid research, [online] 2(1), pp.139–154. doi:https://doi.org/10.1089/can.2016.0034.
  5. ‌Office (2023). What to Know About Products Containing Cannabis and CBD. [online] U.S. Food and Drug Administration. Available at: https://www.fda.gov/consumers/consumer-updates/what-you-need-know-and-what-were-working-find-out-about-products-containing-cannabis-or-cannabis#:~:text=CBD%20has%20the%20potential%20to,potentially%20causing%20serious%20side%20effects.
  6. ‌Anand, U., Pacchetti, B., Anand, P. and Sodergren, M.H. (2021). Cannabis-based medicines and pain: a review of potential synergistic and entourage effects. Pain management, [online] 11(4), pp.395–403. doi:https://doi.org/10.2217/pmt-2020-0110.
  7. ‌Kazuaki Shinomiya, Inoue, T., Yoshiaki Utsu, Tokunaga, S., Masuoka, T., Asae Ohmori and Kamei, C. (2005). Hypnotic Activities of Chamomile and Passiflora Extracts in Sleep-Disturbed Rats. Biological & Pharmaceutical Bulletin, [online] 28(5), pp.808–810. doi:https://doi.org/10.1248/bpb.28.808.
  8. ‌Lalanne, S., Fougerou‐Leurent, C., Anderson, G.M., Schröder, C., Nir, T., Chokron, S., Delorme, R., Bruno, C., Éric Bellissant, Solenn Kermarrec, Franco, P., Denis, L. and Tordjman, S. (2021). Melatonin: From Pharmacokinetics to Clinical Use in Autism Spectrum Disorder. International Journal of Molecular Sciences, [online] 22(3), pp.1490–1490. doi:https://doi.org/10.3390/ijms22031490.
  9. ‌Corroon, J. (2021). Cannabinol and Sleep: Separating Fact from Fiction. Cannabis and cannabinoid research. [online] doi:https://doi.org/10.1089/can.2021.0006.
  10. ‌Kim, S., Jo, K., Kyung Taek Hong, Sung Hee Han and Hyung Joo Suh (2019). GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. Pharmaceutical Biology, [online] 57(1), pp.64–72. doi:https://doi.org/10.1080/13880209.2018.1557698.
  11. ‌Stanciu, C.N., Brunette, M.F., Teja, N. and Budney, A.J. (2021). Evidence for Use of Cannabinoids in Mood Disorders, Anxiety Disorders, and PTSD: A Systematic Review. Psychiatric Services, [online] 72(4), pp.429–436. doi:https://doi.org/10.1176/appi.ps.202000189.
  12. ‌Rao, T.P., Ozeki, M. and Lekh Raj Juneja (2015). In Search of a Safe Natural Sleep Aid. Journal of The American College of Nutrition, [online] 34(5), pp.436–447. doi:https://doi.org/10.1080/07315724.2014.926153.
  13. ‌Finan, P.H., Goodin, B.R. and Smith, M.T. (2013). The Association of Sleep and Pain: An Update and a Path Forward. The Journal of Pain, [online] 14(12), pp.1539–1552. doi:https://doi.org/10.1016/j.jpain.2013.08.007.
  14. ‌Porter, B., Barbara St. Marie, Milavetz, G. and Herr, K. (2021). Cannabidiol (CBD) Use by Older Adults for Acute and Chronic Pain. Journal of Gerontological Nursing, [online] 47(7), pp.6–15. doi:https://doi.org/10.3928/00989134-20210610-02.
  15. ‌Wright, M., Patricia Di Ciano and Brands, B. (2020). Use of Cannabidiol for the Treatment of Anxiety: A Short Synthesis of Pre-Clinical and Clinical Evidence. Cannabis and cannabinoid research, [online] 5(3), pp.191–196. doi:https://doi.org/10.1089/can.2019.0052.
  16. ‌Shannon, S., Lewis, N., Lee, H. and Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente Journal, [online] 23(1). doi:https://doi.org/10.7812/tpp/18-041.
  17. ‌Sinemyiz Atalay, Iwona Jarocka-Karpowicz and Elżbieta Skrzydlewska (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants, [online] 9(1), pp.21–21. doi:https://doi.org/10.3390/antiox9010021.
Kate Barrington

Medically reviewed by:

Kathy Shattler

Kate Barrington holds a Bachelor’s degree in English and is the published author of several self-help books and nutrition guides. Also an avid dog lover and adoring owner of three cats, Kate’s love for animals has led her to a successful career as a freelance writer specializing in pet care and nutrition. Kate holds a certificate in fitness nutrition and enjoys writing about health and wellness trends — she also enjoys crafting original recipes. In addition to her work as a ghostwriter and author, Kate is also a blogger for a number of organic and natural food companies as well as a columnist for several pet magazines.

Medically reviewed by:

Kathy Shattler

Journal of Physical Education and Sport

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American Board of Family Medicine

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Informit

RMIT University Library

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European Food Safety Authority

Science, Safe food, Sustainability

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American Academy of Orthopaedic Surgeons

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American Academy of Family Physicians

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Agricultural Research Service

U.S. Department of Agriculture

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The American Journal of Medicine

Official Journal of The Alliance for Academic Internal Medicine

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National Institute on Alcohol Abuse and Alcoholism

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Lippincott Journals

Subsidiaries of Wolters Kluwer Health, Inc.

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National Institute on Aging

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Translational Research

The Journal of Laboratory and Clinical Medicine

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Cell

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Journal of Translational Medicine

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Federal Trade Commission

Protecting America's Consumers

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National Human Genome Research Institute

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Food Production, Processing and Nutrition

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BMC Gastroenterology

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ACS Publications

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Annual Reviews

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PubChem

National Center for Biotechnology Information

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Peer-reviewed & Open Access Journal

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European Journal of Agriculture and Food Sciences

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Chemical Science Journals, Books and Database

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Frontiers

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German Scholarly Publishing House

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Hindawi

Open Access Research Journals & Papers

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Oilseeds and Fats, Crops and Lipids

EDP Sciences

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Cambridge Core

Cambridge University Press

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FoodData Central

U.S. Department Of Agriculture

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Journal of the American Heart Association

Peer-reviewed Open Access Scientific Journal

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Journal of the Academy of Nutrition and Dietetics

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United Kingdom's National Academy of Sciences

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Peer-reviewed And Refereed Journal

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Peer-reviewed Bimonthly Journal

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American Psychological Association

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MDPI

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Bulletin of the National Research Centre

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The New England Journal of Medicine

Massachusetts Medical Society

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Economic Research Service

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The BMJ

Weekly Peer-reviewed Medical Trade Journal

The British Medical Association
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The British Psychological Society

The British Psychological Society is a charity registered in England

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National Heart, Lung, and Blood Institute

Database From National Institute Of Health

U.S Department of Health and Human Services
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PubMed

Database From National Institute Of Health

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DailyMed

Database From National Institute Of Health

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Google Scholar

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Science.gov: USA.gov for Science

Government Science Portal

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ResearchGate

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American Heart Association

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BioMed Central

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JAMA Network

Home of JAMA and the Specialty Journals of the American Medical Association

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Springer Link

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ODS

Database from Office of Dietary Supplements

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Federal Trade Commission

Bureaus of Consumer Protection, Competition and Economics
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Database From U.S. Department of Health & Human Services

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Oxford Academic Journals

Oxford University Press

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Taylor & Francis Online

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WHO

Database from World Health Organization

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Journal of Neurology

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American Academy of Neurology Journal
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ScienceDirect

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American Multinational Publishing Company

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Centers for Disease Control and Prevention

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